FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SF3b130
反应性
Human,Mouse
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
140kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SF3B3. AA range:231-280
特异性
SF3b130 Polyclonal Antibody detects endogenous levels of SF3b130 protein.
基因名称
SF3B3
蛋白名称
Splicing factor 3B subunit 3
别名
SF3B3;KIAA0017;SAP130;Splicing factor 3B subunit 3;Pre-mRNA-splicing factor SF3b 130 kDa subunit;SF3b130;STAF130;Spliceosome-associated protein 130;SAP 130
Organism-1
Human
基因ID-1
23450
SwissProt-1
Q15393
Organism-2
Mouse
基因ID-2
101943
SwissProt-2
Q921M3
背景
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus .
