FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SETMAR
反应性
Human,Rat,Mouse,
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
77kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SETMAR. AA range:350-400
特异性
SETMAR Polyclonal Antibody detects endogenous levels of SETMAR protein.
基因名称
SETMAR
蛋白名称
Histone-lysine N-methyltransferase SETMAR
别名
SETMAR;Histone-lysine N-methyltransferase SETMAR;SET domain and mariner transposase fusion gene-containing protein;HsMar1;Metnase
Organism-1
Human
基因ID-1
6419
SwissProt-1
Q53H47
Organism-2
Mouse
SwissProt-2
Q80UJ9
背景
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],
细胞定位
Nucleus . Chromosome . Recruited on damaged DNA at sites of double-strand breaks. .
