FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SERCA1
反应性
Human,Mouse,Rat,Salamander,Pig
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
100kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ATP2A1. AA range:548-597
特异性
SERCA1 Polyclonal Antibody detects endogenous levels of SERCA1 protein.
基因名称
ATP2A1
蛋白名称
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
别名
ATP2A1;Sarcoplasmic/endoplasmic reticulum calcium ATPase 1;SERCA1;SR Ca;2+;-ATPase 1;Calcium pump 1;Calcium-transporting ATPase sarcoplasmic reticulum type;fast twitch skeletal muscle isoform;Endoplasmic reticulum class 1/2 Ca;2+;AT
Organism-1
Human
基因ID-1
487
SwissProt-1
O14983
Organism-2
Mouse
基因ID-2
11937
SwissProt-2
Q8R429
Organism-3
Rat
基因ID-3
116601
SwissProt-3
Q64578
背景
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Oct 2013],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Sarcoplasmic reticulum membrane ; Multi-pass membrane protein .
