FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Septin 5
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from Septin 5 . at AA range: 180-260
特异性
Septin 5 Polyclonal Antibody detects endogenous levels of Septin 5 protein.
基因名称
SEPT5
蛋白名称
Septin-5
别名
SEPT5;PNUTL1;Septin-5;Cell division control-related protein 1;CDCrel-1;Peanut-like protein 1
Organism-1
Human
基因ID-1
5413
SwissProt-1
Q99719
Organism-2
Mouse
基因ID-2
18951
SwissProt-2
Q9Z2Q6
Organism-3
Rat
基因ID-3
116728
SwissProt-3
Q9JJM9
背景
septin 5(SEPT5) Homo sapiens This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010],
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . In platelets, found in areas surrounding alpha-granules.
