Sclerostin Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2616168
- 产品信息
商品描述
靶点-Target
Sclerostin
反应性
Human,Rat,Mouse,
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
26kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from Sclerostin . at AA range: 130-210
特异性
Sclerostin Polyclonal Antibody detects endogenous levels of Sclerostin protein.
基因名称
SOST
蛋白名称
Sclerostin
别名
SOST;Sclerostin
Organism-1
Human
基因ID-1
50964
SwissProt-1
Q9BQB4
Organism-2
Mouse
SwissProt-2
Q99P68
背景
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease. [provided by RefSeq, Jul 2008],
细胞定位
Secreted, extracellular space, extracellular matrix .





