- 产品信息
商品描述
靶点-Target
Sar1B
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
22kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SAR1B. AA range:111-160
特异性
Sar1B Polyclonal Antibody detects endogenous levels of Sar1B protein.
基因名称
SAR1B
蛋白名称
GTP-binding protein SAR1b
别名
SAR1B;SARA2;SARB;GTP-binding protein SAR1b;GTP-binding protein B;GTBPB
Organism-1
Human
基因ID-1
51128
SwissProt-1
Q9Y6B6
Organism-2
Mouse
基因ID-2
66397
SwissProt-2
Q9CQC9
Organism-3
Rat
基因ID-3
287276
SwissProt-3
Q5HZY2
背景
The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010],
细胞定位
Endoplasmic reticulum membrane ; Peripheral membrane protein . Golgi apparatus, Golgi stack membrane ; Peripheral membrane protein . Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region. .





