FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Saposin
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
58kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PSAP. AA range:307-356
特异性
Saposin Polyclonal Antibody detects endogenous levels of Saposin protein.
基因名称
PSAP
蛋白名称
Proactivator polypeptide
别名
PSAP;GLBA;SAP1;Proactivator polypeptide
Organism-1
Human
基因ID-1
5660
SwissProt-1
P07602
Organism-2
Mouse
SwissProt-2
Q61207
背景
This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016],
细胞定位
Lysosome .; [Prosaposin]: Secreted . Secreted as a fully glycosylated 70 kDa protein composed of complex glycans. .
