- 产品信息
商品描述
靶点-Target
SAP 49
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
55kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SF3B4. AA range:61-110
特异性
SAP 49 Polyclonal Antibody detects endogenous levels of SAP 49 protein.
基因名称
SF3B4
蛋白名称
Splicing factor 3B subunit 4
别名
SF3B4;SAP49;Splicing factor 3B subunit 4;Pre-mRNA-splicing factor SF3b 49 kDa subunit;SF3b50;Spliceosome-associated protein 49;SAP 49
Organism-1
Human
基因ID-1
10262
SwissProt-1
Q15427
Organism-2
Mouse
基因ID-2
107701
SwissProt-2
Q8QZY9
Organism-3
Rat
基因ID-3
295270
SwissProt-3
Q6AYL5
背景
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus .





