SAP 49 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616156

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商品描述
  • 靶点-Target

    SAP 49

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    55kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human SF3B4. AA range:61-110

  • 特异性

    SAP 49 Polyclonal Antibody detects endogenous levels of SAP 49 protein.

  • 基因名称

    SF3B4

  • 蛋白名称

    Splicing factor 3B subunit 4

  • 别名

    SF3B4;SAP49;Splicing factor 3B subunit 4;Pre-mRNA-splicing factor SF3b 49 kDa subunit;SF3b50;Spliceosome-associated protein 49;SAP 49

  • Organism-1

    Human

  • 基因ID-1

    10262

  • SwissProt-1

    Q15427

  • Organism-2

    Mouse

  • 基因ID-2

    107701

  • SwissProt-2

    Q8QZY9

  • Organism-3

    Rat

  • 基因ID-3

    295270

  • SwissProt-3

    Q6AYL5

  • 背景

    This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Nucleus .