- 产品信息
商品描述
靶点-Target
SAE1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human AOS1. AA range:221-270
特异性
SAE1 Polyclonal Antibody detects endogenous levels of SAE1 protein.
基因名称
SAE1
蛋白名称
SUMO-activating enzyme subunit 1
别名
SAE1;AOS1;SUA1;UBLE1A;SUMO-activating enzyme subunit 1;Ubiquitin-like 1-activating enzyme E1A
Organism-1
Human
基因ID-1
10055
SwissProt-1
Q9UBE0
Organism-2
Mouse
基因ID-2
56459
SwissProt-2
Q9R1T2
Organism-3
Rat
基因ID-3
308384
SwissProt-3
Q6AXQ0
背景
SUMO1 activating enzyme subunit 1(SAE1) Homo sapiens Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010],
细胞定位
Nucleus .





