FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
S2P
反应性
Human,Mouse,Rat
应用
WB,IP,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
57kD
推荐稀释比
WB 1:500-2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MBTPS2. AA range:301-350
特异性
S2P Polyclonal Antibody detects endogenous levels of S2P protein.
基因名称
MBTPS2
蛋白名称
Membrane-bound transcription factor site-2 protease
别名
MBTPS2;S2P;Membrane-bound transcription factor site-2 protease;Endopeptidase S2P;Sterol regulatory element-binding proteins intramembrane protease;SREBPs intramembrane protease
Organism-1
Human
基因ID-1
51360
SwissProt-1
O43462
Organism-2
Mouse
基因ID-2
270669
SwissProt-2
Q8CHX6
背景
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009],
细胞定位
Membrane ; Multi-pass membrane protein . Cytoplasm .
