- 产品信息
商品描述
靶点-Target
RyR-2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
200-300kD
推荐稀释比
WB 1:500-2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RyR2. AA range:2774-2823
特异性
RyR-2 Polyclonal Antibody detects endogenous levels of RyR-2 protein.
基因名称
RYR2
蛋白名称
Ryanodine receptor 2
别名
RYR2;Ryanodine receptor 2;RYR-2;RyR2;hRYR-2;Cardiac muscle ryanodine receptor;Cardiac muscle ryanodine receptor-calcium release channel;Type 2 ryanodine receptor
Organism-1
Human
基因ID-1
6262
SwissProt-1
Q92736
Organism-2
Mouse
基因ID-2
20191
SwissProt-2
E9Q401
Organism-3
Rat
基因ID-3
689560
SwissProt-3
B0LPN4
背景
This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008],
细胞定位
Sarcoplasmic reticulum membrane ; Multi-pass membrane protein . Membrane ; Multi-pass membrane protein . Sarcoplasmic reticulum . The number of predicted transmembrane domains varies between orthologs, but both N-terminus and C-terminus seem to be cytoplasmic. .





