- 产品信息
商品描述
靶点-Target
RORα
反应性
Human,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RORA. AA range:6-55
特异性
RORα Polyclonal Antibody detects endogenous levels of RORα protein.
基因名称
RORA
蛋白名称
Nuclear receptor ROR-alpha
别名
RORA;NR1F1;RZRA;Nuclear receptor ROR-alpha;Nuclear receptor RZR-alpha;Nuclear receptor subfamily 1 group F member 1;Retinoid-related orphan receptor-alpha
Organism-1
Human
基因ID-1
6095
SwissProt-1
P35398
Organism-2
Mouse
SwissProt-2
P51448
背景
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014],
细胞定位
Nucleus .





