- 产品信息
商品描述
靶点-Target
Rock-2
反应性
Human,Mouse,Rat,Monkey
应用
IF,WB,IHC,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
165kD
推荐稀释比
IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;ICC 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ROCK2. AA range:691-740
特异性
Rock-2 Polyclonal Antibody detects endogenous levels of Rock-2 protein.
基因名称
ROCK2
蛋白名称
Rho-associated protein kinase 2
别名
ROCK2;KIAA0619;Rho-associated protein kinase 2;Rho kinase 2;Rho-associated;coiled-coil-containing protein kinase 2;Rho-associated, coiled-coil-containing protein kinase II;ROCK-II;p164 ROCK-2
Organism-1
Human
基因ID-1
9475
SwissProt-1
O75116
Organism-2
Mouse
基因ID-2
19878
SwissProt-2
P70336
Organism-3
Rat
基因ID-3
25537
SwissProt-3
Q62868
背景
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Cell membrane ; Peripheral membrane protein . Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic, and associated with actin microfilaments and the plasma membrane. .





