FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
RO60
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TROVE2. AA range:311-360
特异性
RO60 Polyclonal Antibody detects endogenous levels of RO60 protein.
基因名称
TROVE2
蛋白名称
60 kDa SS-A/Ro ribonucleoprotein
别名
TROVE2;RO60;SSA2;60 kDa SS-A/Ro ribonucleoprotein;60 kDa Ro protein;60 kDa ribonucleoprotein Ro;RoRNP;Ro 60 kDa autoantigen;Sjoegren syndrome antigen A2;Sjoegren syndrome type A antigen;SS-A;TROVE domain family member 2
Organism-1
Human
基因ID-1
6738
SwissProt-1
P10155
Organism-2
Mouse
SwissProt-2
O08848
背景
disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign.,function:RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the Ro 60 kDa family.,similarity:Contains 1 TROVE domain.,subunit:Found in a complex with PUF60 and Y5 RNA. Interacts with RIP11.,
细胞定位
Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. .
