FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
RNase Z2
反应性
Human,Rat,Mouse,
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
92kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ELAC2. AA range:161-210
特异性
RNase Z2 Polyclonal Antibody detects endogenous levels of RNase Z2 protein.
基因名称
ELAC2
蛋白名称
Zinc phosphodiesterase ELAC protein 2
别名
ELAC2;HPC2;Zinc phosphodiesterase ELAC protein 2;ElaC homolog protein 2;Heredity prostate cancer protein 2;Ribonuclease Z 2;RNase Z 2;tRNA 3 endonuclease 2;tRNase Z 2
Organism-1
Human
基因ID-1
60528
SwissProt-1
Q9BQ52
Organism-2
Mouse
SwissProt-2
Q80Y81
背景
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
细胞定位
Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid . Nucleus . Mainly mitochondrial.
