FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
M-RIP
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
115kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human M-RIP.
特异性
M-RIP Polyclonal Antibody detects endogenous levels of M-RIP protein.
基因名称
MPRIP
蛋白名称
Myosin phosphatase Rho-interacting protein
别名
MPRIP;KIAA0864;MRIP;RHOIP3;Myosin phosphatase Rho-interacting protein;M-RIP;Rho-interacting protein 3;RIP3;p116Rip
Organism-1
Human
基因ID-1
23164;23164
SwissProt-1
Q6WCQ1
Organism-2
Mouse
基因ID-2
26936
SwissProt-2
P97434
Organism-3
Rat
基因ID-3
116504
SwissProt-3
Q9ERE6
背景
function:Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.,similarity:Contains 1 PH domain.,similarity:Contains 2 PH domains.,subcellular location:Colocalizes with F-actin.,subunit:Binds F-actin through its N-terminus (By similarity). Binds RHOA, PPP1R12A/MBS and PPP1R12C/MBS85 through adjacent coiled coil domains.,
细胞定位
Cytoplasm, cytoskeleton . Colocalizes with F-actin.
