Ribosomal Protein S19 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2616081

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商品描述
  • 靶点-Target

    Ribosomal Protein S19

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    16kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human RPS19. AA range:81-130

  • 特异性

    Ribosomal Protein S19 Polyclonal Antibody detects endogenous levels of Ribosomal Protein S19 protein.

  • 基因名称

    RPS19

  • 蛋白名称

    40S ribosomal protein S19

  • 别名

    RPS19;40S ribosomal protein S19

  • Organism-1

    Human

  • 基因ID-1

    6223

  • SwissProt-1

    P39019

  • Organism-2

    Mouse

  • 基因ID-2

    20085

  • SwissProt-2

    Q9CZX8

  • Organism-3

    Rat

  • 基因ID-3

    100910336

  • SwissProt-3

    P17074

  • 背景

    Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins

  • 细胞定位

    Nucleus . Located more specifically in the nucleoli.