- 产品信息
商品描述
靶点-Target
RGS12
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
160kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RGS12. AA range:141-190
特异性
RGS12 Polyclonal Antibody detects endogenous levels of RGS12 protein.
基因名称
RGS12
蛋白名称
Regulator of G-protein signaling 12
别名
RGS12;Regulator of G-protein signaling 12;RGS12
Organism-1
Human
基因ID-1
6002
SwissProt-1
O14924
Organism-2
Mouse
基因ID-2
71729
SwissProt-2
Q8CGE9
Organism-3
Rat
基因ID-3
54292
SwissProt-3
O08774
背景
This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . Cell projection, dendrite . Cell junction, synapse .; [Isoform 5]: Nucleus matrix . Also localized to discrete nuclear foci that are distinct from sites of RNA processing, PML nuclear bodies, and PcG domains. .





