FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
RGS1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
22kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RGS1. AA range:118-167
特异性
RGS1 Polyclonal Antibody detects endogenous levels of RGS1 protein.
基因名称
RGS1
蛋白名称
Regulator of G-protein signaling 1
别名
RGS1;1R20;BL34;IER1;Regulator of G-protein signaling 1;RGS1;B-cell activation protein BL34;Early response protein 1R20
Organism-1
Human
基因ID-1
5996
SwissProt-1
Q08116
Organism-2
Mouse
基因ID-2
50778
SwissProt-2
Q9JL25
Organism-3
Rat
基因ID-3
54289
SwissProt-3
P97844
背景
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytosol .
