- 产品信息
商品描述
靶点-Target
RFC2
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
40kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RFC2. AA range:131-180
特异性
RFC2 Polyclonal Antibody detects endogenous levels of RFC2 protein.
基因名称
RFC2
蛋白名称
Replication factor C subunit 2
别名
RFC2;Replication factor C subunit 2;Activator 1 40 kDa subunit;A1 40 kDa subunit;Activator 1 subunit 2;Replication factor C 40 kDa subunit;RF-C 40 kDa subunit;RFC40
Organism-1
Human
基因ID-1
5982
SwissProt-1
P35250
Organism-2
Mouse
基因ID-2
19718
SwissProt-2
Q9WUK4
Organism-3
Rat
基因ID-3
116468
SwissProt-3
Q641W4
背景
This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2. [provided by RefSeq, Jul 2013],
细胞定位
Nucleus .





