FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Repac
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RAPGEF5. AA range:431-480
特异性
Repac Polyclonal Antibody detects endogenous levels of Repac protein.
基因名称
RAPGEF5
蛋白名称
Rap guanine nucleotide exchange factor 5
别名
RAPGEF5;GFR;KIAA0277;MRGEF;Rap guanine nucleotide exchange factor 5;Guanine nucleotide exchange factor for Rap1;M-Ras-regulated Rap GEF;MR-GEF;Related to Epac;Repac
Organism-1
Human
基因ID-1
9771
SwissProt-1
Q92565
Organism-2
Mouse
基因ID-2
217944
SwissProt-2
Q8C0Q9
Organism-3
Rat
基因ID-3
362799
SwissProt-3
P83900
背景
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008],
细胞定位
Nucleus.
