- 产品信息
商品描述
靶点-Target
Reg IV
反应性
Human,Rat,Mouse,
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
18kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human Reg IV.
特异性
Reg IV Polyclonal Antibody detects endogenous levels of Reg IV protein.
基因名称
REG4
蛋白名称
Regenerating islet-derived protein 4
别名
REG4;GISP;RELP;Regenerating islet-derived protein 4;REG-4;Gastrointestinal secretory protein;REG-like protein;Regenerating islet-derived protein IV;Reg IV
Organism-1
Human
基因ID-1
83998
SwissProt-1
Q9BYZ8
Organism-2
Mouse
SwissProt-2
Q9D8G5
背景
function:May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.,induction:Up-regulated by mucosal injury from active Crohn's disease or ulcerative colitis. Up-regulated in colorectal tumors. Up-regulated in epithelial cells at regenerating margins of peptic ulcers in the stomach and duodenum.,online information:Regenerating protein IV,similarity:Contains 1 C-type lectin domain.,tissue specificity:Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentialy expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.,
细胞定位
Secreted .





