- 产品信息
商品描述
靶点-Target
RECK
反应性
Human,Mouse
应用
IHC,IF,WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
110kD
推荐稀释比
WB 1:500-2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RECK. AA range:21-70
特异性
RECK Polyclonal Antibody detects endogenous levels of RECK protein.
基因名称
RECK
蛋白名称
Reversion-inducing cysteine-rich protein with Kazal motifs
别名
RECK;ST15;Reversion-inducing cysteine-rich protein with Kazal motifs;hRECK;Suppressor of tumorigenicity 15 protein
Organism-1
Human
基因ID-1
8434
SwissProt-1
O95980
Organism-2
Mouse
基因ID-2
53614
SwissProt-2
Q9Z0J1
背景
The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],
细胞定位
Cell membrane ; Lipid-anchor, GPI-anchor .





