R-cadherin Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2615988
- 产品信息
商品描述
靶点-Target
R-cadherin
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
100kD
推荐稀释比
IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CDH4. AA range:731-780
特异性
R-cadherin Polyclonal Antibody detects endogenous levels of R-cadherin protein.
基因名称
CDH4
蛋白名称
Cadherin-4
别名
CDH4;Cadherin-4;Retinal cadherin;R-CAD;R-cadherin
Organism-1
Human
基因ID-1
1002
SwissProt-1
P55283
Organism-2
Mouse
基因ID-2
12561
SwissProt-2
P39038
背景
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
细胞定位
Cell membrane; Single-pass type I membrane protein.





