R-cadherin Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615988

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商品描述
  • 靶点-Target

    R-cadherin

  • 反应性

    Human,Mouse

  • 应用

    IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    100kD

  • 推荐稀释比

    IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human CDH4. AA range:731-780

  • 特异性

    R-cadherin Polyclonal Antibody detects endogenous levels of R-cadherin protein.

  • 基因名称

    CDH4

  • 蛋白名称

    Cadherin-4

  • 别名

    CDH4;Cadherin-4;Retinal cadherin;R-CAD;R-cadherin

  • Organism-1

    Human

  • 基因ID-1

    1002

  • SwissProt-1

    P55283

  • Organism-2

    Mouse

  • 基因ID-2

    12561

  • SwissProt-2

    P39038

  • 背景

    This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

  • 细胞定位

    Cell membrane; Single-pass type I membrane protein.