- 产品信息
商品描述
靶点-Target
RBQ-3
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
59kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from RBQ-3 . at AA range: 190-270
特异性
RBQ-3 Polyclonal Antibody detects endogenous levels of RBQ-3 protein.
基因名称
RBBP5
蛋白名称
Retinoblastoma-binding protein 5
别名
RBBP5;RBQ3;Retinoblastoma-binding protein 5;RBBP-5;Retinoblastoma-binding protein RBQ-3
Organism-1
Human
基因ID-1
5929
SwissProt-1
Q15291
Organism-2
Mouse
基因ID-2
213464
SwissProt-2
Q8BX09
背景
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010],
细胞定位
Nucleus .





