- 产品信息
商品描述
靶点-Target
RARβ
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Retinoic Acid Receptor beta. AA range:331-380
特异性
RARβ Polyclonal Antibody detects endogenous levels of RARβ protein.
基因名称
RARB
蛋白名称
Retinoic acid receptor beta
别名
RARB;HAP;NR1B2;Retinoic acid receptor beta;RAR-beta;HBV-activated protein;Nuclear receptor subfamily 1 group B member 2;RAR-epsilon
Organism-1
Human
基因ID-1
5915
SwissProt-1
P10826
Organism-2
Mouse
基因ID-2
218772
SwissProt-2
P22605
背景
This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014],
细胞定位
Nucleus . Cytoplasm .; [Isoform Beta-1]: Nucleus.; [Isoform Beta-2]: Nucleus.; [Isoform Beta-4]: Cytoplasm.





