RARβ Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615974

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商品描述
  • 靶点-Target

    RARβ

  • 反应性

    Human,Mouse

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    50kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Retinoic Acid Receptor beta. AA range:331-380

  • 特异性

    RARβ Polyclonal Antibody detects endogenous levels of RARβ protein.

  • 基因名称

    RARB

  • 蛋白名称

    Retinoic acid receptor beta

  • 别名

    RARB;HAP;NR1B2;Retinoic acid receptor beta;RAR-beta;HBV-activated protein;Nuclear receptor subfamily 1 group B member 2;RAR-epsilon

  • Organism-1

    Human

  • 基因ID-1

    5915

  • SwissProt-1

    P10826

  • Organism-2

    Mouse

  • 基因ID-2

    218772

  • SwissProt-2

    P22605

  • 背景

    This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014],

  • 细胞定位

    Nucleus . Cytoplasm .; [Isoform Beta-1]: Nucleus.; [Isoform Beta-2]: Nucleus.; [Isoform Beta-4]: Cytoplasm.