- 产品信息
商品描述
靶点-Target
Rag B
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
43kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from Rag B . at AA range: 50-130
特异性
Rag B Polyclonal Antibody detects endogenous levels of Rag B protein.
基因名称
RRAGB
蛋白名称
Ras-related GTP-binding protein B
别名
RRAGB;Ras-related GTP-binding protein B;Rag B;RagB
Organism-1
Human
基因ID-1
10325
SwissProt-1
Q5VZM2
Organism-2
Mouse
基因ID-2
245670
SwissProt-2
Q6NTA4
Organism-3
Rat
基因ID-3
100909655
SwissProt-3
Q63487
背景
Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Lysosome .





