FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Raftlin
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
65kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RFTN1. AA range:432-481
特异性
Raftlin Polyclonal Antibody detects endogenous levels of Raftlin protein.
基因名称
RFTN1
蛋白名称
Raftlin
别名
RFTN1;KIAA0084;MIG2;Raftlin;Cell migration-inducing gene 2 protein;Raft-linking protein
Organism-1
Human
基因ID-1
23180
SwissProt-1
Q14699
Organism-2
Mouse
SwissProt-2
Q6A0D4
背景
function:May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor-mediated signaling.,similarity:Belongs to the raftlin family.,subcellular location:Associates with lipid rafts.,tissue specificity:Specifically expressed by B-cells (at protein level).,
细胞定位
Cell membrane ; Lipid-anchor . Cytoplasm . Membrane raft . Endosome . Early endosome . Translocates from cytoplasm to cell membrane where it colocalizes with poly (I:C) and then moves to endosomes where it colocalizes with TLR3 (PubMed:21266579). Translocates from cytoplasm to cell membrane where it colocalizes with TLR4 and then together with TLR4 moves to endosomes, upon lipopolysaccharide stimulation (PubMed:27022195). .
