Rad51B Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615946

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商品描述
  • 靶点-Target

    Rad51B

  • 反应性

    Human,Mouse,Monkey

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    45kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human RAD51L1. AA range:201-250

  • 特异性

    Rad51B Polyclonal Antibody detects endogenous levels of Rad51B protein.

  • 基因名称

    RAD51B

  • 蛋白名称

    DNA repair protein RAD51 homolog 2

  • 别名

    RAD51B;RAD51L1;REC2;DNA repair protein RAD51 homolog 2;R51H2;RAD51 homolog B;Rad51B;RAD51-like protein 1

  • Organism-1

    Human

  • 基因ID-1

    5890

  • SwissProt-1

    O15315

  • Organism-2

    Mouse

  • 基因ID-2

    19363

  • SwissProt-2

    O35719

  • 背景

    RAD51 paralog B(RAD51B) Homo sapiens The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016],

  • 细胞定位

    Nucleus .