- 产品信息
商品描述
靶点-Target
Rad51B
反应性
Human,Mouse,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
45kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RAD51L1. AA range:201-250
特异性
Rad51B Polyclonal Antibody detects endogenous levels of Rad51B protein.
基因名称
RAD51B
蛋白名称
DNA repair protein RAD51 homolog 2
别名
RAD51B;RAD51L1;REC2;DNA repair protein RAD51 homolog 2;R51H2;RAD51 homolog B;Rad51B;RAD51-like protein 1
Organism-1
Human
基因ID-1
5890
SwissProt-1
O15315
Organism-2
Mouse
基因ID-2
19363
SwissProt-2
O35719
背景
RAD51 paralog B(RAD51B) Homo sapiens The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016],
细胞定位
Nucleus .





