FGF-2 Polyclonal Antibody
¥680.00
Rabaptin-5α Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2615930
- 产品信息
商品描述
靶点-Target
Rabaptin-5α
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
99kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RABEP1. AA range:549-598
特异性
Rabaptin-5α Polyclonal Antibody detects endogenous levels of Rabaptin-5α protein.
基因名称
RABEP1
蛋白名称
Rab GTPase-binding effector protein 1
别名
RABEP1;RAB5EP;RABPT5;RABPT5A;Rab GTPase-binding effector protein 1;Rabaptin-4;Rabaptin-5;Rabaptin-5alpha;Renal carcinoma antigen NY-REN-17
Organism-1
Human
基因ID-1
9135
SwissProt-1
Q15276
Organism-2
Mouse
基因ID-2
54189
SwissProt-2
O35551
Organism-3
Rat
基因ID-3
54190
SwissProt-3
O35550
背景
function:Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.,PTM:Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity.,similarity:Belongs to the rabaptin family.,subunit:Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2.,
细胞定位
Cytoplasm. Early endosome. Recycling endosome. Cytoplasmic vesicle.
