FGF-2 Polyclonal Antibody
¥680.00
Rab11-FIP3 Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2615927
- 产品信息
商品描述
靶点-Target
Rab11-FIP3
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
82kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RAB11FIP3. AA range:569-618
特异性
Rab11-FIP3 Polyclonal Antibody detects endogenous levels of Rab11-FIP3 protein.
基因名称
RAB11FIP3
蛋白名称
Rab11 family-interacting protein 3
别名
RAB11FIP3;ARFO1;KIAA0665;Rab11 family-interacting protein 3;FIP3-Rab11;Rab11-FIP3;Arfophilin-1;EF hands-containing Rab-interacting protein;Eferin;MU-MB-17.148
Organism-1
Human
基因ID-1
9727
SwissProt-1
O75154
Organism-2
Mouse
基因ID-2
215445
SwissProt-2
Q8CHD8
背景
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008],
细胞定位
Recycling endosome membrane ; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cleavage furrow . Midbody . In early mitosis remains diffuse and distributed through the cell. The onset of anaphase sequesters these vesicles to the centrosomes at the opposite poles of the cell. During telophase these vesicles move from the centrosomes, to the furrow, and then to the midbody to aid in abscission (PubMed:15158446, PubMed:15601896, PubMed:18511905). Interaction with Rab11 mediates localization to endosomes (PubMed:11495908). Interaction with ARF6 mediates localization to the midbody (PubMed:16148947). .
