FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Rab 6A
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
24kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RAB6A. AA range:113-162
特异性
Rab 6A Polyclonal Antibody detects endogenous levels of Rab 6A protein.
基因名称
RAB6A
蛋白名称
Ras-related protein Rab-6A
别名
RAB6A;RAB6;Ras-related protein Rab-6A;Rab-6
Organism-1
Human
基因ID-1
5870
SwissProt-1
P20340
Organism-2
Mouse
基因ID-2
19346
SwissProt-2
P35279
Organism-3
Rat
SwissProt-3
Q9WVB1
背景
This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011],
细胞定位
Golgi apparatus membrane ; Lipid-anchor . BICD2 facilitates its targeting to Golgi apparatus membrane. .; [Isoform 1]: Golgi apparatus membrane ; Lipid-anchor .; [Isoform 2]: Golgi apparatus membrane ; Lipid-anchor .
