FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Rab 38
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
26kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RAB38. AA range:80-129
特异性
Rab 38 Polyclonal Antibody detects endogenous levels of Rab 38 protein.
基因名称
RAB38
蛋白名称
Ras-related protein Rab-38
别名
RAB38;Ras-related protein Rab-38;Melanoma antigen NY-MEL-1
Organism-1
Human
基因ID-1
23682
SwissProt-1
P57729
Organism-2
Mouse
基因ID-2
72433
SwissProt-2
Q8QZZ8
背景
function:May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1.,PTM:Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated.,similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Expressed in melanocytes.,
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Melanosome membrane . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991). .
