Rab 3 GAP p150 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615910

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商品描述
  • 靶点-Target

    Rab 3 GAP p150

  • 反应性

    Human,Mouse,Rat,Monkey

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    156kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human RAB3GAP2. AA range:417-466

  • 特异性

    Rab 3 GAP p150 Polyclonal Antibody detects endogenous levels of Rab 3 GAP p150 protein.

  • 基因名称

    RAB3GAP2

  • 蛋白名称

    Rab3 GTPase-activating protein non-catalytic subunit

  • 别名

    RAB3GAP2;KIAA0839;Rab3 GTPase-activating protein non-catalytic subunit;RGAP-iso;Rab3 GTPase-activating protein 150 kDa subunit;Rab3-GAP p150;Rab3-GAP150;Rab3-GAP regulatory subunit

  • Organism-1

    Human

  • 基因ID-1

    25782

  • SwissProt-1

    Q9H2M9

  • Organism-2

    Mouse

  • 基因ID-2

    98732

  • SwissProt-2

    Q8BMG7

  • Organism-3

    Rat

  • 基因ID-3

    289350

  • SwissProt-3

    Q5U1Z0

  • 背景

    The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009],

  • 细胞定位

    Cytoplasm. In neurons, it is enriched in the synaptic soluble fraction.