Rab 3 GAP p130 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2615909
- 产品信息
商品描述
靶点-Target
Rab 3 GAP p130
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
117kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RAB3GAP1. AA range:538-587
特异性
Rab 3 GAP p130 Polyclonal Antibody detects endogenous levels of Rab 3 GAP p130 protein.
基因名称
RAB3GAP1
蛋白名称
Rab3 GTPase-activating protein catalytic subunit
别名
RAB3GAP1;KIAA0066;RAB3GAP;Rab3 GTPase-activating protein catalytic subunit;RAB3 GTPase-activating protein 130 kDa subunit;Rab3-GAP p130;Rab3-GAP
Organism-1
Human
基因ID-1
22930
SwissProt-1
Q15042
Organism-2
Mouse
SwissProt-2
Q80UJ7
背景
This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010],
细胞定位
Cytoplasm . In neurons, it is enriched in the synaptic soluble fraction.





