Rab 3 GAP p130 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615909

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商品描述
  • 靶点-Target

    Rab 3 GAP p130

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    117kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human RAB3GAP1. AA range:538-587

  • 特异性

    Rab 3 GAP p130 Polyclonal Antibody detects endogenous levels of Rab 3 GAP p130 protein.

  • 基因名称

    RAB3GAP1

  • 蛋白名称

    Rab3 GTPase-activating protein catalytic subunit

  • 别名

    RAB3GAP1;KIAA0066;RAB3GAP;Rab3 GTPase-activating protein catalytic subunit;RAB3 GTPase-activating protein 130 kDa subunit;Rab3-GAP p130;Rab3-GAP

  • Organism-1

    Human

  • 基因ID-1

    22930

  • SwissProt-1

    Q15042

  • Organism-2

    Mouse

  • SwissProt-2

    Q80UJ7

  • 背景

    This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010],

  • 细胞定位

    Cytoplasm . In neurons, it is enriched in the synaptic soluble fraction.