- 产品信息
商品描述
靶点-Target
PU.1
反应性
Human,Mouse,Rat,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
32kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human SPI1. AA range:181-230
特异性
PU.1 Polyclonal Antibody detects endogenous levels of PU.1 protein.
基因名称
SPI1
蛋白名称
Transcription factor PU.1
别名
SPI1;Transcription factor PU.1;31 kDa-transforming protein
Organism-1
Human
基因ID-1
6688
SwissProt-1
P17947
Organism-2
Mouse
基因ID-2
20375
SwissProt-2
P17433
Organism-3
Rat
基因ID-3
366126
SwissProt-3
Q6BDS1
背景
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus .





