FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PRX III
反应性
Human,Mouse,Rat
应用
WB,IHC,IP,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
26kD
推荐稀释比
WB 1:500-1:2000;IHC:1:50-300;IP 1:50-200;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PRX III. AA range:44-93
特异性
PRX III Polyclonal Antibody detects endogenous levels of PRX III protein.
基因名称
PRDX3
蛋白名称
Thioredoxin-dependent peroxide reductase mitochondrial
别名
PRDX3;AOP1;Thioredoxin-dependent peroxide reductase;mitochondrial;Antioxidant protein 1;AOP-1;HBC189;Peroxiredoxin III;Prx-III;Peroxiredoxin-3;Protein MER5 homolog
Organism-1
Human
基因ID-1
10935
SwissProt-1
P30048
Organism-2
Mouse
基因ID-2
11757
SwissProt-2
P20108
Organism-3
Rat
基因ID-3
64371
SwissProt-3
Q9Z0V6
背景
This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. [provided by RefSeq, Oct 2014],
细胞定位
Mitochondrion . Cytoplasm . Early endosome . Localizes to early endosomes in a RPS6KC1-dependent manner. .
