PRX II Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615864

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商品描述
  • 靶点-Target

    PRX II

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    21kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from the C-terminal region of human PRX II.

  • 特异性

    PRX II Polyclonal Antibody detects endogenous levels of PRX II protein.

  • 基因名称

    PRDX2

  • 蛋白名称

    Peroxiredoxin-2

  • 别名

    PRDX2;NKEFB;TDPX1;Peroxiredoxin-2;Natural killer cell-enhancing factor B;NKEF-B;PRP;Thiol-specific antioxidant protein;TSA;Thioredoxin peroxidase 1;Thioredoxin-dependent peroxide reductase 1

  • Organism-1

    Human

  • 基因ID-1

    7001

  • SwissProt-1

    P32119

  • Organism-2

    Mouse

  • 基因ID-2

    21672

  • SwissProt-2

    Q61171

  • Organism-3

    Rat

  • 基因ID-3

    29338

  • SwissProt-3

    P35704

  • 背景

    This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013],

  • 细胞定位

    Cytoplasm .