- 产品信息
商品描述
靶点-Target
PRX II
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
21kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the C-terminal region of human PRX II.
特异性
PRX II Polyclonal Antibody detects endogenous levels of PRX II protein.
基因名称
PRDX2
蛋白名称
Peroxiredoxin-2
别名
PRDX2;NKEFB;TDPX1;Peroxiredoxin-2;Natural killer cell-enhancing factor B;NKEF-B;PRP;Thiol-specific antioxidant protein;TSA;Thioredoxin peroxidase 1;Thioredoxin-dependent peroxide reductase 1
Organism-1
Human
基因ID-1
7001
SwissProt-1
P32119
Organism-2
Mouse
基因ID-2
21672
SwissProt-2
Q61171
Organism-3
Rat
基因ID-3
29338
SwissProt-3
P35704
背景
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013],
细胞定位
Cytoplasm .





