- 产品信息
商品描述
靶点-Target
PRP19
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PRPF19. AA range:171-220
特异性
PRP19 Polyclonal Antibody detects endogenous levels of PRP19 protein.
基因名称
PRPF19
蛋白名称
Pre-mRNA-processing factor 19
别名
PRPF19;NMP200;PRP19;SNEV;Pre-mRNA-processing factor 19;Nuclear matrix protein 200;PRP19/PSO4 homolog;hPso4;Senescence evasion factor
Organism-1
Human
基因ID-1
27339
SwissProt-1
Q9UMS4
Organism-2
Mouse
基因ID-2
28000
SwissProt-2
Q99KP6
Organism-3
Rat
基因ID-3
246216
SwissProt-3
Q9JMJ4
背景
PSO4 is the human homolog of yeast Pso4, a gene essential for cell survival and DNA repair (Beck et al., 2008 [PubMed 18263876]).[supplied by OMIM, Sep 2008],
细胞定位
Nucleus . Nucleus, nucleoplasm . Cytoplasm, cytoskeleton, spindle . Cytoplasm . Lipid droplet . Nucleoplasmic in interphase cells. Irregularly distributed in anaphase cells. In prophase cells, uniformly distributed, but not associated with condensing chromosomes. Found in extrachromosomal regions in metaphase cells. Mainly localized to the mitotic spindle apparatus when chromosomes segregate during anaphase. When nuclei reform during late telophase, uniformly distributed in daughter cells and displays no preferred association with decondensing chromatin. Recruited on damaged DNA at sites of double-strand break. .





