- 产品信息
商品描述
靶点-Target
PRDM3
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
18kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MECOM. AA range:1-50
特异性
PRDM3 Polyclonal Antibody detects endogenous levels of PRDM3 protein.
基因名称
MECOM
蛋白名称
MDS1 and EVI1 complex locus protein MDS1
别名
MECOM;MDS1;MDS1 and EVI1 complex locus protein MDS1;Myelodysplasia syndrome 1 protein;Myelodysplasia syndrome-associated protein 1
Organism-1
Human
基因ID-1
4197
SwissProt-1
Q13465
Organism-2
Mouse
SwissProt-2
Q9Z1L8
背景
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],
细胞定位
histone deacetylase complex,nucleus,nucleoplasm,cytoplasm,Golgi apparatus,cytosol,aggresome,nuclear speck,intracellular membrane-bounded organelle,





