PRDM3 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615847

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商品描述
  • 靶点-Target

    PRDM3

  • 反应性

    Human,Rat,Mouse,

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    18kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human MECOM. AA range:1-50

  • 特异性

    PRDM3 Polyclonal Antibody detects endogenous levels of PRDM3 protein.

  • 基因名称

    MECOM

  • 蛋白名称

    MDS1 and EVI1 complex locus protein MDS1

  • 别名

    MECOM;MDS1;MDS1 and EVI1 complex locus protein MDS1;Myelodysplasia syndrome 1 protein;Myelodysplasia syndrome-associated protein 1

  • Organism-1

    Human

  • 基因ID-1

    4197

  • SwissProt-1

    Q13465

  • Organism-2

    Mouse

  • SwissProt-2

    Q9Z1L8

  • 背景

    The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],

  • 细胞定位

    histone deacetylase complex,nucleus,nucleoplasm,cytoplasm,Golgi apparatus,cytosol,aggresome,nuclear speck,intracellular membrane-bounded organelle,