- 产品信息
商品描述
靶点-Target
PPAR α
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
52kD
推荐稀释比
WB 1:500-2000;ELISA 1:10000-20000;IHC 1:50-300;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PPAR-alpha. AA range:6-55
特异性
PPAR-α Polyclonal Antibody detects endogenous levels of PPAR-α protein.
基因名称
PPARA
蛋白名称
Peroxisome proliferator-activated receptor alpha
别名
PPARA;NR1C1;PPAR;Peroxisome proliferator-activated receptor alpha;PPAR-alpha;Nuclear receptor subfamily 1 group C member 1
Organism-1
Human
基因ID-1
5465
SwissProt-1
Q07869
Organism-2
Mouse
基因ID-2
19013
SwissProt-2
P23204
Organism-3
Rat
基因ID-3
25747
SwissProt-3
P37230
背景
peroxisome proliferator activated receptor alpha(PPARA) Homo sapiens Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for thi
细胞定位
Nucleus.





