FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PP2Cε
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PPM1L. AA range:119-168
特异性
PP2Cε Polyclonal Antibody detects endogenous levels of PP2Cε protein.
基因名称
PPM1L
蛋白名称
Protein phosphatase 1L
别名
PPM1L;PP2CE;Protein phosphatase 1L;Protein phosphatase 1-like;Protein phosphatase 2C isoform epsilon;PP2C-epsilon
Organism-1
Human
基因ID-1
151742
SwissProt-1
Q5SGD2
Organism-2
Mouse
基因ID-2
242083
SwissProt-2
Q8BHN0
背景
The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],
细胞定位
Membrane ; Single-pass type I membrane protein .
