PP2A-B56-α Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2615825

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商品描述
  • 靶点-Target

    PP2A-B56-α

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    57kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human PPP2R5A. AA range:321-370

  • 特异性

    PP2A-B56-α Polyclonal Antibody detects endogenous levels of PP2A-B56-α protein.

  • 基因名称

    PPP2R5A

  • 蛋白名称

    Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

  • 别名

    PPP2R5A;Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform;PP2A B subunit isoform B'-alpha;PP2A B subunit isoform B56-alpha;PP2A B subunit isoform PR61-alpha;PR61alpha;PP2A B subunit isoform R5-alpha

  • Organism-1

    Human

  • 基因ID-1

    5525

  • SwissProt-1

    Q15172

  • Organism-2

    Mouse

  • 基因ID-2

    226849

  • SwissProt-2

    Q6PD03

  • 背景

    The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010],

  • 细胞定位

    Cytoplasm . Nucleus . Chromosome, centromere . From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase. .