FGF-2 Polyclonal Antibody
¥680.00
PP2A-B55-β Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2615824
- 产品信息
商品描述
靶点-Target
PP2A-B55-β
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
51kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from PP2A-B55-β . at AA range: 90-170
特异性
PP2A-B55-β Polyclonal Antibody detects endogenous levels of PP2A-B55-β protein.
基因名称
PPP2R2B
蛋白名称
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
别名
PPP2R2B;Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform;PP2A subunit B isoform B55-beta;PP2A subunit B isoform PR55-beta;PP2A subunit B isoform R2-beta;PP2A subunit B isoform beta
Organism-1
Human
基因ID-1
5521
SwissProt-1
Q00005
Organism-2
Mouse
基因ID-2
72930
SwissProt-2
Q6ZWR4
Organism-3
Rat
基因ID-3
60660
SwissProt-3
P36877
背景
protein phosphatase 2 regulatory subunit Bbeta(PPP2R2B) Homo sapiens The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isofor
细胞定位
[Isoform 1]: Cytoplasm . Cytoplasm, cytoskeleton . Membrane .; [Isoform 2]: Cytoplasm . Mitochondrion . Mitochondrion outer membrane . Under basal conditions, localizes to both cytosolic and mitochondrial compartments. Relocalizes from the cytosolic to the mitochondrial compartment during apoptosis. Its targeting to the outer mitochondrial membrane (OMM) involves an association with import receptors of the TOM complex and is required to promote proapoptotic activity (By similarity). .
