FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PP2A-Aβ
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
66kD
推荐稀释比
WB 1:500-1:2000;IHC:1:50-300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PPP2R1B. AA range:552-601
特异性
PP2A-Aβ Polyclonal Antibody detects endogenous levels of PP2A-Aβ protein.
基因名称
PPP2R1B
蛋白名称
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
别名
PPP2R1B;Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform;PP2A subunit A isoform PR65-beta;PP2A subunit A isoform R1-beta
Organism-1
Human
基因ID-1
5519
SwissProt-1
P30154
Organism-2
Mouse
基因ID-2
73699
SwissProt-2
Q7TNP2
Organism-3
Rat
基因ID-3
315648
SwissProt-3
Q4QQT4
背景
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010],
细胞定位
membrane raft,extracellular exosome,
