FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
POT1
反应性
Human,Monkey
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human POT1. AA range:247-296
特异性
POT1 Polyclonal Antibody detects endogenous levels of POT1 protein.
基因名称
POT1
蛋白名称
Protection of telomeres protein 1
别名
POT1;Protection of telomeres protein 1;hPot1;POT1-like telomere end-binding protein
Organism-1
Human
基因ID-1
25913
SwissProt-1
Q9NUX5
Organism-2
Mouse
SwissProt-2
Q91WC1
背景
protection of telomeres 1(POT1) Homo sapiens This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Chromosome, telomere . Colocalizes with telomeric DNA.
