FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
POLR3C
反应性
Human,Rat,Mouse,
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RPC3. AA range:191-240
特异性
POLR3C Polyclonal Antibody detects endogenous levels of POLR3C protein.
基因名称
POLR3C
蛋白名称
DNA-directed RNA polymerase III subunit RPC3
别名
POLR3C;DNA-directed RNA polymerase III subunit RPC3;RNA polymerase III subunit C3;DNA-directed RNA polymerase III subunit C;RNA polymerase III 62 kDa subunit;RPC62
Organism-1
Human
基因ID-1
10623
SwissProt-1
Q9BUI4
Organism-2
Mouse
SwissProt-2
Q9D483
背景
disease:Antibodies against POLR3C were found in the sera of patients with systemic sclerosis (SSc).,function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation.,similarity:Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). RPC3/POLR3C, RPC6/POLR3F and RPC7/POLR3G form a Pol III subcomplex. Interacts with GTF3C4.,
细胞定位
Nucleus .
