- 产品信息
商品描述
靶点-Target
POLR2E
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
25kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human RPAB1. AA range:21-70
特异性
POLR2E Polyclonal Antibody detects endogenous levels of POLR2E protein.
基因名称
POLR2E
蛋白名称
DNA-directed RNA polymerases I, II, and III subunit RPABC1
别名
POLR2E;DNA-directed RNA polymerases I;II, and III subunit RPABC1;RNA polymerases I, II, and III subunit ABC1;DNA-directed RNA polymerase II 23 kDa polypeptide;DNA-directed RNA polymerase II subunit E;RPB5 homolog;XAP4
Organism-1
Human
基因ID-1
5434
SwissProt-1
P19388
Organism-2
Mouse
基因ID-2
66420
SwissProt-2
Q80UW8
Organism-3
Rat
基因ID-3
690966
SwissProt-3
B0BNE2
背景
This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],
细胞定位
Nucleus .





