- 产品信息
商品描述
靶点-Target
POLR1E
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
49kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the Internal region of human POLR1E.
特异性
POLR1E Polyclonal Antibody detects endogenous levels of POLR1E protein.
基因名称
POLR1E
蛋白名称
DNA-directed RNA polymerase I subunit RPA49
别名
POLR1E;PAF53;PRAF1;DNA-directed RNA polymerase I subunit RPA49;RNA polymerase I subunit A49;DNA-directed RNA polymerase I subunit E;RNA polymerase I-associated factor 1;RNA polymerase I-associated factor 53
Organism-1
Human
基因ID-1
64425
SwissProt-1
Q9GZS1
Organism-2
Mouse
SwissProt-2
Q8K202
背景
function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF.,similarity:Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.,subunit:Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits (By similarity). Interacts with PAF49/CD3EAP. Also binds UBTF/UBF.,
细胞定位
Nucleus, nucleolus .





