- 产品信息
商品描述
靶点-Target
PNPase
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
85kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human PNPT1. AA range:570-619
特异性
PNPase Polyclonal Antibody detects endogenous levels of PNPase protein.
基因名称
PNPT1
蛋白名称
Polyribonucleotide nucleotidyltransferase 1 mitochondrial
别名
PNPT1;PNPASE;Polyribonucleotide nucleotidyltransferase 1;mitochondrial;3'-5' RNA exonuclease OLD35;PNPase old-35;Polynucleotide phosphorylase 1;PNPase 1;Polynucleotide phosphorylase-like protein
Organism-1
Human
基因ID-1
87178
SwissProt-1
Q8TCS8
Organism-2
Mouse
基因ID-2
71701
SwissProt-2
Q8K1R3
背景
The protein encoded by this gene belongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. This enzyme is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7. [provided by RefSeq, Dec 2012],
细胞定位
Cytoplasm . Mitochondrion matrix . Mitochondrion intermembrane space ; Peripheral membrane protein .





